As people age, systemic inflammation can inflict degenerative effects throughout the body.1-5 A primary cause of this destructive cascade is the production of cell-signaling chemicals known as inflammatory cytokines. Along with these dangerous cytokines, imbalances of hormone-like messengers called prostaglandins also contribute to inflammatory processes. As people grow older, structural alterations occur in their joints that lead to discomfort and loss of mobility. While conventional doctors rely on prescription drugs, scientists have identified a number of natural agents that provide broad-spectrum support for healthy joint function and structure.* Glucosamine provides the underlying structural foundation for joints,9 while methylsulfonylmethane (MSM) provides crucial sulfur compounds that are so important to maintain comfortable joint function.10* Nobiletin is a citrus flavonoid that has demonstrated potent effects in suppressing destructive cytokines such as tumor necrosis factor alpha and interleukin-1 beta.11 In addition, nobiletin has demonstrated natural COX-2 inhibiting properties without affecting beneficial COX-1. Suppression of the COX-2 enzyme limits the production of joint damaging prostaglandin E2.12 A special Boswellia extract known as 5-Loxin® inhibits the 5-lipoxygenase enzyme, reducing levels of joint damaging leukotriene B4.13* ArthroMax™ has been enhanced with FruiteX B® OsteoBoron™, a patented form of boron that is chemically identical to the natural plant forms of boron found in food. Considered safer and more bioavailable than other forms of boron, FruiteX B® OsteoBoron™ not only supports strong bones but healthy joints! Boron is a micronutrient that has been used historically as a nutritional supplement to promote healthy bones and joints, possibly by down-regulating inflammation through the NF-(Kappa)b pathway. ArthroMax™ combines these potent nutrients into one convenient formula for healthy joints.* | 
