Biotin is an unnumbered member of the B-complex family, normallyonly required in minute amounts. Biotin, a water-soluble vitamin, isused as cofactor of enzymes involved in fatty acid metabolism,gluconeogenesis, and amino acid catabolism, making biotin essential inmaintaining metabolic homeostasis. Biotin plays an important role inmetabolic functioning as a coenzyme carrier of activated carbon dioxidein the TCA cycle (also known as the Krebs cycle).232In its coenzyme form, biotin synthesizes glucose from noncarbohydratesources, and synthesizes and breaks down certain fatty acids and aminoacids.232 |
