Natural Strategies for Alleviating Cancer Symptoms
A range of complementary strategies are known to improve symptoms experienced by cancer patients.
Anxiety, Depression, and Stress. The use of
aromatherapy and massage is effective in alleviating depression,
anxiety, and stress in cancer patients and has a positive effect on
quality of life (Cassileth BR et al 2004; Soden K et al 2004).
Undergoing 30-minute massage sessions three times a week for five weeks
reduces hostility and anger in cancer patients (Hernandez-Reif M et al
2004). In addition to massage, progressive muscle relaxation alleviates
depression and anxiety in cancer patients (Hernandez-Reif M et al
2005).
The use of acupuncture, hypnosis, and exercise reduces stress and
anxiety (Samuels N 2002; Stalpers LJ et al 2005; Thorsen L et al 2005).
Laughter and humor are also known to improve mood and combat
depression in cancer patients (Bennett MP et al 2003; Christie W et al
2005; Takahashi K et al 2001). This improvement in mood is accompanied
by quantifiable improvements in immune system and hormonal factors that
influence overall well-being (Berk LS et al 2001; Christie W et al
2005; Takahashi K et al 2001).
Emotional support from a spouse reduces depression and improves
quality of life in cancer patients (Ohara-Hirano Y et al 2004). Dietary
supplementation with the amino acid L-carnitine in cancer patients has
been effective in treating depression (Cruciani RA et al 2004).
Nausea and Vomiting. Acupuncture and finger
acupressure are effective in overcoming treatment-induced nausea and
vomiting (Collins KB et al 2004; Klein J et al 2004; Shin YH et al
2004). Electro-acupoint stimulation and hypnotherapy also reduce the
frequency and intensity of nausea in cancer patients (Gan TJ et al
2004; Deng G et al 2004).
Poor Appetite/Cachexia. Advanced cancer is often
accompanied by a condition of muscle wasting referred to as cachexia or
catabolic wasting (Barber MD 2001; Brown TT et al 2003). Metabolic
imbalances caused by the disease, which include the over-production of
inflammatory factors, lead to the loss of appetite and the excessive
breakdown of fat and muscle (Barber MD et al 2001). This wasting
condition is associated with diminished quality of life and shorter
survival (Barber MD 2001; Brown TT et al 2003).
Dietary supplementation with fish oils (omega-3 fatty acids)
counteracts the inflammatory factors and reverses the weight loss
associated with cachexia (Barber MD 2001; Brown TT et al 2003; Fearon
KC et al 2003). Stabilization of this condition with fish oil
supplements also leads to enhanced quality of life (Bruera E et al
2003; Burns CP et al 2004; Fearon KC et al 2003). For more information,
refer to the chapter on Catabolic Wasting.
Lymphedema. Lymphedema, a condition characterized
by excessive swelling and retention of water under the skin, often
afflicts cancer patients, particularly after radiation therapy and
surgery (Ashikaga T et al 2002; McNeely ML et al 2004).
Natural strategies known to be somewhat helpful in alleviating this
condition include compression bandaging, which reduces the size of the
swollen area, and manual massage of the draining lymph nodes, which may
alleviate mild cases of lymphedema (McNeely ML et al 2004; Mortimer PS
1997). The use of selenium may improve the benefits of physical
therapies such as massage and compression (Bruns F et al 2003).
Sexual Dysfunction. Cancer patients, in particular
those with prostate cancer, often experience sexual dysfunction, or
impotency, usually as a complication of their treatment (Burnett AL
2005; Jayne DG et al 2005; Turner SL et al 1999). Sexual dysfunction is
also associated with surgery for bladder and colorectal cancer, and
with chemotherapy agents that damage the ovaries (Jayne DG et al 2005;
Molina JR et al 2005).
Sexual dysfunction in prostate cancer patients can be successfully
managed by the use of Viagra® (Incrocci L et al 2003a; Incrocci L et al
2003b). However, some alternative therapies are also effective in
managing sexual dysfunction.
Clinical studies have shown that oral supplements of L-glutamine and
yohimbine, a plant extract, can improve erectile dysfunction (Lebret T
et al 2002). Another dietary supplement known as ArginMax™, which
contains a combination of ginseng, ginkgo, L-arginine, multivitamins,
and minerals, improves erectile dysfunction (Ito T et al 1998, 2001). A
nutritional supplement known as Kyo-Green® has also been shown to
improve sexual dysfunction (Lau BH et al 2003).
Hair Loss. A mushroom extract, originally concocted
for use as an immune system booster, improves alopecia (hair loss), a
condition associated with the use of conventional cancer treatments
(Ahn WS et al 2004). Animal studies have also shown that supplementing
with the antioxidant N-acetylcysteine can also protect against hair
loss during conventional cancer treatments (D'Agostini F et al 1998).
Fatigue. In addition to relieving stress, dietary
supplementation with the amino acid L-carnitine reduces fatigue, which
can be a symptom of the cancer or a side effect of conventional
treatment (Cruciani RA et al 2004). The use of L-carnitine during
chemotherapy with doxorubicin has been proposed as an adjuvant therapy
since 1985 (de Leonardis V et al 1985).
Acupuncture has also demonstrated effectiveness in alleviating
cancer fatigue (Cohen AJ et al 2005). Cancer-related fatigue responds
to a combined regimen of massage, foot soaking, and reflexology (Kohara
H et al 2004). In addition, breathing exercises, conducted with the
help of a healthcare provider, improves fatigue in patients recovering
from stem cell transplantation (Kim SD et al 2005).
Natural Strategies for Counteracting Adverse Effects from Conventional Cancer Treatment
Nutritional supplements known to counteract some of the negative
side effects of conventional treatments are summarized in Table 2. In
addition to these nutrients, physical and psychological
therapies—including acupuncture, breathing exercises, massage and
aromatherapy—can also improve these negative side effects (Fellowes D
et al 2004; Kim SD et al 2005; Samuels N 2002). For more information,
refer to the chapters on Cancer Surgery, Cancer Chemotherapy, and
Cancer Radiation Therapy.
Table 2: Nutritional supplements known to alleviate negative side effects of conventional cancer treatment
|
Cancer Treatment-Related Adverse Effects |
Nutritional Supplement |
References |
|
Diarrhea, neuropathy, heart complications, mucositis |
Glutamine |
(Daniele B et al 2001; Savarese DM et al 2003) |
|
Mucositis, fibrosis, cardiovascular complications |
Antioxidants |
(Borek C 2004; Wattanapitayakul SK et al 2005) |
|
Mucositis, anemia, cardiovascular complications |
Melatonin |
(Majsterek I et al 2005; Ahmed HH et al 2005; Balli E et al 2004) |
|
Radiation-induced cell damage |
Vitamin A |
(Levitsky J et al 2003; Vorotnikova E et al 2004). |
|
Neuropathy (nerve damage) |
Vitamin E |
(Argyriou AA et al 2005; Pace A et al 2003) |
|
Nausea and vomiting |
Ginger |
(Boon H et al 2004; Sharma SS et al 1998; Manusirivithaya S et al 2004). |
|
Nephrotoxicity (kidney damage) |
Silibinin |
(Bokemeyer C et al 1996) |
|
Diarrhea |
Herbal Remedies |
(Mori K et al 2003; Taixiang W et al 2005) |
|
Heart damage |
CoQ10 |
(Portakal O et al 2000; Bandy B et al 1990; Iarussi D et al 1994). |
Clinical Trials
Numerous ongoing clinical studies are assessing the merits of
different CAM therapies for cancer. Cancer patients can opt to
participate in these studies or simply monitor their outcomes. The
specific details and findings of these studies are subject to constant
change and therefore are not provided here. Up-to-date information on
ongoing clinical trials can be obtained from the National Center for
Complementary and Alternative Medicine (NCCAM) at the following address:
NCCAM
National Institutes of Health
Bethesda, MD 20892
Email: info@nccam.nih.gov.
Website: http://nccam.nih.gov/clinicaltrials/
Vitamin Depot Online.com Foundation Recommendations
Cancer patients should consult their physicians before using any
complementary alternative therapies while undergoing conventional
medical treatment.
Different doses of the same nutritional supplement may be required
for different applications of complementary alternative cancer
therapies, such as preventing cancer, inhibiting tumor spread,
enhancing/suppressing the immune system, alleviating cancer symptoms,
and counteracting the side effects of conventional treatment. Cancer
patients who wish to adopt a CAM approach should refer to the
appropriate chapter or consult an integrative practitioner for
definitive advice on appropriate doses of the nutritional supplements
discussed in this chapter. |
Product Availability
All the nutrients and supplements discussed in this section are
available through the Vitamin Depot Online.com Foundation Buyers Club, Inc. For
ordering information, call anytime toll-free 1-800-544-4440, or visit
us online at www.LifeExtension.com.
The blood tests discussed in this section are available through Life
Extension National Diagnostics, Inc. For ordering information, call
anytime toll-free 1-800-208-3444, or visit us online at
www.LifeExtension.com.
Safety Caveats
Patients should consult physicians who are qualified integrative practitioners experienced in the field of nutritional oncology. |