The vascular endothelium is the inner lining of blood vessels that regulates arterial and venous health. The reason for many circulatory problems is the breakdown of endothelial function and structure. Fortunately, there are nutrients that have been clinically shown to help maintain healthy endothelial function and arterial circulation.

Pomegranate promotes cardiovascular health

In a group of aging humans with risk factors for cardiovascular events, pomegranate or a placebo was ingested daily. Both groups continued taking their conventional medications. After twelve months, carotid artery conditions (measured as carotid intima-media thickness) were improved30% in the pomegranate group while carotid artery conditions worsenedby9% in the placebo group.38 Additionally, in those who consumed pomegranate, total antioxidant status was increasedby130% while blood serum levels of LDL basal oxidative state and LDL susceptibility to oxidation were both significantly reduced by90% and 59% respectively.

In a similar study, pomegranate or a placebo was ingested daily. After only three months, coronary artery blood flow improvedby18% in the pomegranate group but worsenedby 17% in the placebo group.39

A next-generation pomegranate extract, blending standardized extracts from the whole fruit, flower and seed oil, is one of the active components of EndothelialDefense™ formula. Full-Spectrum Pomegranate™ provides this fruit’s unique polyphenols with newly discovered biologically active compounds from other parts of the pomegranate plant.

SODprotectsagainstnitricoxidedegradation

Aging reduces the body’s production of a critical antioxidant called superoxide dismutase (SOD), which provides the body’s first enzymatic step in the defense system against oxidative stress. Diminished SOD levels are closely linked with increased vascular oxidative stress, which contributes to endothelial dysfunction.46 An orally active superoxide dismutase (SOD) called GliSODin® has been clinicallyshown to support healthy arterial function and structure, while boosting levels of the body’s most powerful antioxidant enzymes (SOD and catalase) and protecting against oxidative stress-induced cell death.47-50

Studies show that carotid artery thickness detrimentally increases by 0.04 mm every ten years. However, a recent study with GliSODin® suggests that 2.8 years of supplementation may turn back the clock on 10 years of age-related damage due to carotid artery wall thickening.15 Endothelial Defense™ formula contains GliSODin® in a dose identical to that which was used in this successful human study.

Endothelial Defense™ provides the best-documented nutrients to help you maintain healthy arterial blood flow and normal blood pressure.

POMELLA® Extract is covered under U.S. Patent 7,638,640 and POMELLA® is a registered trademark of Verdure Sciences, Inc.
Isocell SA, France is the owner of US Patents Nos. 6,045,809 and 6,426,068B1 and trademark of GliSODin®.