Melatonin is a pineal hormone that has been widely studied for its
ability to produce sleep. In the body, melatonin is secreted in
response to darkness, causing sleepiness.
Because so many patients with fibromyalgia have insomnia or
unrefreshing sleep, researchers have sought to determine whether
melatonin can be of specific help to them as a sleep agent. Studies
have found that people with fibromyalgia have low melatonin levels.
Supplementation with melatonin resulted in improved sleep and lowered
requirements for prescription drugs (Rohr UD et al 2002). A Swedish
study determined that patients with fibromyalgia produce less melatonin
during hours of darkness than do healthy control subjects, making
melatonin therapy potentially helpful as a sleep aid (Wikner J et al
1998). Researchers in Argentina conducted a pilot study in which they
found that sleep patterns, sleep quality, and pain measures markedly
improve in patients with fibromyalgia after 4 weeks of treatment with
melatonin (Citera G et al 2000). In the United States, a double-blind,
placebo-controlled study showed that 20 percent of the patients with
fibromyalgia significantly improved their sleep patterns and quality
when they took 6 mg of melatonin each night before bed.
Diet and Lifestyle Approaches
Patients with fibromyalgia can do a number of things to help
diminish their pain, deepen their sleep, and generally improve their
quality of life.
Diet. No controlled studies have been undertaken to
date to test whether specific foods can alleviate symptoms of
fibromyalgia. The following dietary guidelines may help patients with
fibromyalgia (Hanninen O et al 2000):
Consume plenty of calcium to support bone density. Foods high in
calcium include milk, ice cream, yogurt, broccoli, hard cheeses,
oysters, sardines, spinach, and oranges.
Apples are high in malic acid, an antioxidant important in limiting muscle pain.
Blueberries have been shown by the USDA to be higher in antioxidants than any other fruit, vegetable, nut, or herb.
Carbohydrates increase serotonin levels, essential fatty acids
reduce fatigue, and protein helps improve mental alertness (Wallace D
et al 2002).
Caffeine, a strong stimulant, should be avoided,
particularly late in the day, to ensure that it does not negatively
affect sleep.
Alcohol should never be used to alleviate or mask pain.
Exercise. Moderate, regular exercise has been
shown to reduce symptoms. Patients with fibromyalgia should work some
of the following exercises into their schedule:
Walk 20 to 40 minutes daily. Walking—outdoors when possible—is perhaps the best regular exercise.
Swim 30 to 60 minutes three times a week. Swimming can successfully strengthen and tone painful muscles.
Do isometric and stretching exercises. These types of
exercises, particularly those focused on muscle groups susceptible to
fibromyalgia pain, are vitally important.
Strengthen and stretch muscles through yoga. Yoga is also an
excellent way to engage with other people and take your mind off pain.
Maintain good posture at all times. Don’t stay in a single position for long periods.
Use supports such as armrests, railings, pillows, and slings to help avoid needlessly stressing sensitive muscles.
Focus as much as possible on relaxation and stress reduction.
Deep breathing, meditation, and other forms of conscious relaxation are
often quite helpful.
Tobacco use. People with fibromyalgia should not
smoke or use tobacco. Smokers with fibromyalgia have lower pain
thresholds and more sleep problems than nonsmokers. Nicotine withdrawal
can cause muscle spasms, and vascular constriction is worsened by
smoking, leading to increased numbness, burning, and tingling (Wallace
D et al 2002).
Other Treatments. Many patients with fibromyalgia
report excellent results fighting pain with the help of therapists
trained to use a variety of the following musculoskeletal and
psychological treatments:
Regular massage. Offers significant pain relief.
Chiropractic. Chiropractors work to align the spine for optimal nerve flow and to increase range of motion and relax muscles.
Physical and occupational therapy. Physical and occupational
therapists, particularly those specifically trained to work with
patients who have fibromyalgia, can design rehabilitation programs
involving both manipulation and exercise that often show positive
results.
Acupuncture. A 2500-year-old treatment system, using very
thin needles, that has shown moderate degrees of effectiveness in
treating both pain and fatigue in patients with fibromyalgia.
Psychotherapy, counseling, and support groups. These groups
can be enormously beneficial to people with fibromyalgia, offering
great assistance with issues such as anxiety, loss of self-esteem,
anger, shame, depression, and relationship challenges.
Vitamin Depot Online.com Foundation Recommendations
The Vitamin Depot Online.com Foundation’s approach to fibromyalgia takes into
account the many facets of the disease. The following supplements have
been shown to reduce oxidative stress and inflammation, support healthy
ATP levels in cells, aid in restful sleep and digestion, and support
muscle function:
Vitamin Depot Online.com Mix—Follow label directions. Vitamin Depot Online.com Mix provides a balanced mix of antioxidants and other nutrients.
DHEA—Starting dose of 15 to 75 mg daily. Have blood tested in 3 to 6 weeks to make sure optimal levels are maintained.
In addition to these supplements, hormonal testing is recommended.
If levels are low, bioidentical hormonal replacement may be
recommended. For more information about hormonal testing, call the Life
Extension Foundation at 1-800-544-4440. Patients who are deficient in
growth hormone should consult with a qualified physician.
Finally, patients who have been conventionally treated may have
gastrointestinal problems from the many drugs that are often
prescribed. These drugs may alter the levels of beneficial bacteria in
the gut. For this reason, a person who has fibromyalgia should take
probiotics, including the lactobacillus group of beneficial bacteria,
to restore gastrointestinal function.
Fibromyalgia Safety Caveats
An aggressive program of dietary supplementation should not be
launched without the supervision of a qualified physician. Several of
the nutrients suggested in this protocol may have adverse effects.
These include:
DHEA
Do not take DHEA if you could be pregnant, are breastfeeding, or could have prostate, breast, uterine, or ovarian cancer.
DHEA can cause androgenic effects in woman such as acne, deepening of the voice, facial hair growth and hair loss.
D-Ribose
Do not take D-ribose if you have gout.
Do not take D-ribose if you have elevated uric acid levels. D-ribose can elevate uric acid levels.
Consult your doctor before taking D-ribose if you have
diabetes or hypoglycemia. D-ribose can cause or exacerbate
hypoglycemia. See your doctor and monitor your blood glucose level
frequently if you take D-ribose and have hyperglycemia or diabetes.
EPA/DHA
Consult your doctor before taking EPA/DHA if you take warfarin
(Coumadin). Taking EPA/DHA with warfarin may increase the risk of
bleeding.
Discontinue using EPA/DHA 2 weeks before any surgical procedure.
Magnesium
Do not take magnesium if you have kidney failure or myasthenia gravis.
Melatonin
Do not take melatonin if you are depressed.
Do not take high doses of melatonin if you are trying to
conceive. High doses of melatonin have been shown to inhibit ovulation.
Melatonin can cause morning grogginess, a feeling of having a
hangover or a “heavy head,” or gastrointestinal symptoms such as nausea
and diarrhea.
Vitamin B6
Individuals who are being treated with levodopa without taking
carbidopa at the same time should avoid doses of 5 milligrams or
greater daily of vitamin B6.
Selenium
High doses of selenium (1000 micrograms or more daily) for prolonged periods may cause adverse reactions.
High doses of selenium taken for prolonged periods may cause
chronic selenium poisoning. Symptoms include loss of hair and nails or
brittle hair and nails.
Selenium can cause rash, breath that smells like garlic, fatigue, irritability, and nausea and vomiting.
SODzymes
Do not take SODzymes if you are allergic to soy, corn, or wheat.
Vitamin C
Do not take vitamin C if you have a history of kidney stones or of
kidney insufficiency (defined as having a serum creatine level greater
than 2 milligrams per deciliter and/or a creatinine clearance less than
30 milliliters per minute.
Consult your doctor before taking large amounts of vitamin C
if you have hemochromatosis, thalassemia, sideroblastic anemia, sickle
cell anemia, or erythrocyte glucose-6-phosphate dehydrogenase (G6PD)
deficiency. You can experience iron overload if you have one of these
conditions and use large amounts of vitamin C.
Vitamin E
Consult your doctor before taking vitamin E if you take warfarin (Coumadin).
Consult your doctor before taking high doses of vitamin E if you have a vitamin K deficiency or a history of liver failure.
Consult your doctor before taking vitamin E if you have a
history of any bleeding disorder such as peptic ulcers, hemorrhagic
stroke, or hemophilia.
Discontinue using vitamin E 1 month before any surgical procedure.