For nearly 2800 years the Chinese have used extracts from the Ginkgo bilobatree to treat a variety of conditions to maintain the healthy normalfunction of the brain, cardiovascular, blood and blood vessels,circulatory, and metabolic processes.95-113* Ginkgo may:

• Help to maintain normal circulation95,96*
• Help to maintain the normal function and tone of blood vessels97,98*
• Maintain oxygen and glucose metabolism in the brain99-101*
• Prevent capillary fragility and blood leakage into surrounding tissue99,102*
• Help the normal function of factors that maintain a normal blood flow95-103*
• Maintain normal coagulation of blood104,105*
• Reduce tissue damage caused by low blood flow99,106,107*
• May help control radiation-induced brain edema in-vitro108,109*
• Help slow the aging process in the brain103,110-113*

Ginkgocontains numerous antioxidants such as the proanthocyanidins andflavonoids, which counteract free-radical activity. Flavonoids are alsoknown to strengthen capillaries, which can promote healthy blood flowto the brain, helping to maintain cognitive health.103,110-115*

People often associate ginkgo with healthy cognitive function, but areview of hundreds of published studies reveals that this flavonoidprobably benefits every cell in the body. In addition to maintaininghealthy arterial function116 via several well-defined mechanisms, ginkgo also functions as a platelet aggregation inhibitor.116*

Ginkgo bilobaacts similar to a potent antioxidant and scavenger of most free radicalspecies, such as hydroxyl and peroxyl radicals and superoxide anions.117It is known to protect the energy-producing mitochondria in the cells,thus enhancing oxygen utilization and cellular respiration.117*

Life Extensions Ginkgo Biloba Certified Extract™ contains 24% ginkgoflavone glycosides and 6% terpene lactones. In addition to what iscertified to be in the product, what is not in this extract is alsoimportant. The health regulatory agency that regulates ginkgo purity inGermany mandates that it not contain more than 5 ppm of ginkgolic acid.Life Extensions low-cost ginkgo contains less than 1 ppm of this toxicpart of the ginkgo leaf.

Ginkgo biloba extract is a potent antioxidant and scavenger of mostfree radical species, such as hydroxyl and peroxyl radicals andsuperoxide anions.38 It isknown to protect the energy producing mitochondria within the cells,thus enhancing oxygen utilization and cellular respiration.*

In a study to determine whether ginkgo extract could preventage-associated cellular changes, the brain and liver mitochondria ofold mice fed ginkgo extract in their drinking water was compared tothose of young and old control mice. Mitochondria from the rats givenginkgo exhibited significantly less genetic damage, peroxidegeneration, and oxidation of the crucial antioxidant glutathione thanthe nonsupplemented rats. In addition, mitochondria from the old ratsgiven the ginkgo extract resembled those of the young rats much moreclosely, being similar in size and morphology. The study concluded thatstandardized ginkgo extract prevents age-related decline inmitochondrial structure and function by protecting mitochondria fromoxidative damage.39

The pharmaceutical grade botanical extract in Ginkgo BilobaCertified Extract™ has been concentrated and dual standardized toensure the highest quality, consistency, and biological activity. Thephytonutrient profile of Ginkgo Biloba Certified Extract™ is comparableto the Gbe 24/6 extract used in clinical studies worldwide andmonographed in German Commission E. The health regulatory agency thatregulates ginkgo purity in Germany mandates that ginkgo not containmore than 5 ppm of ginkgolic acid. Ginkgo Biloba Certified ExtractTMcontains less than 1 ppm of this toxic part of the ginkgo leaf.Ginkgolic acid is a substance related to anacardic acid (poison ivy)and may cause an allergic reaction in some people. Ginkgo BilobaCertified Extract™ has the lowest ginkgolic acid level available.

Ginkgo Biloba Certified Extract™ has high levels of ginkgolide B(>0.8%), which is the most studied terpene lactone, and thought tobe a potent inhibitor of platelet activating factor (PAF). PAF is apowerful inflammatory mediator.*

If you are taking anticoagulants or MAO inhibitors, consult yourdoctor before taking ginkgo. Not for use by pregnant or lactatingwomen. Ginkgolic acid is an allergen for some people and is present inmuch higher levels in different quality products.*

There are 120 mg of this standardized ginkgo extract ineach capsule of Life Extension Super Booster. If you take the SuperBooster product, you do not need to take any additional ginkgo.