As people age, chronic systemic inflammation can inflict degenerative effects throughout the body.1-5A primary cause of this destructive cascade is the production ofcell-signaling chemicals known as inflammatory cytokines. Along withthese dangerous cytokines, imbalances of hormone-like messengers calledprostaglandins also contribute to chronic inflammatory processes. The body needs fatty acids to survive and is able to make all buttwo of them: linoleic acid, in the omega-6 family and linolenic acid,in the omega-3 family. These two fatty acids must be supplied by thediet and are therefore considered essential fatty acids (EFAs). Omega-3 fatty acids, found in cold-water fish (and fish oil), andperilla and flaxseed oils, can be part of a healthy diet. Omega-3 oilscontain the essential fatty acids eicosapentaenoic acid (EPA) anddocosahexaenoic acid (DHA), which are usually lacking in the typicalWestern diet that includes high amounts of omega-6 fats.6 Omega-6 fatty acids are well supplied in the diet by meat andvegetable oils. However, not all omega-6 fatty acids are of equalvalue. Gamma linolenic acid (GLA), found in evening primrose oil,borage oil, and black currant oil is an important fatty acid that playsa beneficial role in healthy prostaglandin formation.7*What you eat also contributes to the production of inflammatorycytokines. Eating foods cooked at high temperature can cause theformation of advanced glycation end (AGE) products.8Glycation is the binding of a protein molecule to a glucose moleculethat results in the formation of damaged protein structures. As thedamaged proteins accumulate, they activate the production ofinflammatory cytokines. Presently there is no way to reverse theeffects of glycation. Fatty acids are essential for life. Besides storing energy, thesefats are part of our makeup; they live in our healthy cells, muscles,nerves, and organs. Conversely, there are bad fats that must becontrolled or avoided to maintain good health. The “good” fats are unsaturated fats that are usually from oils ofvegetables, nuts, and some fish. Since they cannot be produced withinthe body, our diets must be EFA-rich. “Bad” fats are saturated fats,typically from animal fats, dairy products, etc. Without adequatelevels of good fats, dangerous saturated fats will replace theessential fatty acids in our cells. Supplementation with the right proportions of fatty acids canmaximize the production of good prostaglandins (E1 and E3), whilelowering the amount of unwanted prostaglandin E2 and leukotriene B4. Inaddition to avoiding saturated fats and high glycemic foods, eatingomega-3 foods, and consuming supplements that provide GLA, DHA, and EPAcan maintain a healthy amount of desirable prostaglandins and therebybring balance to the essential fatty acids.32-38* The essential fatty acids in Super GLA/DHA have been concentratedand standardized in order to ensure quality, potency, and biologicalactivity.
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